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The Best Retinol Creams Available Without a Prescription for Glowing and Healthy Skin

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By Audrey Noble and Genesis Rivas
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The secret to clearer, firmer, and brighter skin lies in a special ingredient: retinol. "Retinol is a vitamin A derivative that exfoliates and stimulates collagen production in the skin," says Sumayah Jamal, MD, board-certified dermatologist at Schweiger Dermatology Group. Not only that, it pretty much addresses every skin concern: It helps stimulate skin cell regeneration, treats hyperpigmentation, brightens, and reduces the appearance of acne scars and fine lines by "telling skin cells to behave like younger, healthier cells," says Dendy Engelman, MD, a board-certified cosmetic dermatologist and Mohs surgeon Shafer Clinic. There are different forms of retinol, and each vary in potency. "Prescription retinoids like tretinoin and tazarotene are the most potent," says Jamal. "Retinaldehyde is available over the counter and is more potent than retinol, which is also available over the counter."

Our Top Picks

  • 1
    Rapid Wrinkle Repair Retinol Face Moisturizer

    Best Drugstore

    Neutrogena Rapid Wrinkle Repair Retinol Face Moisturizer

    $17 at Amazon
    Read more
  • 2
    AlphaRet Overnight Cream

    Best Overall

    Skinbetter AlphaRet Overnight Cream

    Read more
  • 3
    Luna Retinol Sleeping Night Oil

    Best for Redness

    Sunday Riley Luna Retinol Sleeping Night Oil

    Read more
  • 4
    Retinol 0.5 Refining Night Cream

    Best for All Skin Types

    SkinCeuticals Retinol 0.5 Refining Night Cream

    Read more
  • 5
    Retinol Correxion Under Eye Cream

    Best Drugstore for Eyes

    RoC Retinol Correxion Under Eye Cream

    Read more

You can tell how strong the retinol is based on the percentage. "In over-the-counter retinol creams, common percentages of retinol are 0.25 percent, 0.3 percent, 0.5 percent, or 1 percent," says Engelman. "If you are an experienced retinol user, you may be able to use a higher percentage of retinol. If you have very dry or sensitive skin, or are a first-time retinol user, you may want to start out with a low percentage of retinol and increase as the skin adjusts." It’s also a good idea to patch-test any new retinol cream to see how your skin reacts, she recommends. Essentially, everyone can reap the benefits of this gold-standard ingredient, says Howard Sobel, MD, dermatologist and founder of Sobel Skin. Here, the best retinol creams you can buy over the counter.

1
Best Drugstore

Neutrogena Rapid Wrinkle Repair Retinol Face Moisturizer

Rapid Wrinkle Repair Retinol Face Moisturizer
1
Best Drugstore

Neutrogena Rapid Wrinkle Repair Retinol Face Moisturizer

Now 42% Off
$17 at Amazon
Credit: Neutrogena
Pros
  • Affordable
  • Contains SPF
Cons
  • Can only use during day

"Along with a low dose of retinol, it also contains hydrating and calming hyaluronic acid and protective SPF," says Sobel.

2
Best Overall

Skinbetter AlphaRet Overnight Cream

AlphaRet Overnight Cream
2
Best Overall

Skinbetter AlphaRet Overnight Cream

Credit: Skinbetter Science
Pros
  • Evens skin tone and texture
Cons
  • It's a splurge

"Skin Better AlphaRet combines peptides, glycolic acid 10 percent, and vitamin C as well as a retinoid-strength retinol," says Levin. Engleman also loves it because it refines the complexion and evens out skin tone.

3
Best for Redness

Sunday Riley Luna Retinol Sleeping Night Oil

Luna Retinol Sleeping Night Oil
3
Best for Redness

Sunday Riley Luna Retinol Sleeping Night Oil

Credit: Sunday Riley
Pros
  • Soothes redness
  • Hydrating
Cons
  • Not technically a cream

Lee recommends this sleeping night oil as another good bet for dry skin because of the avocado seed oil. Blue tansy and German chamomile make it great for soothing redness.

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4
Best for All Skin Types

SkinCeuticals Retinol 0.5 Refining Night Cream

Retinol 0.5 Refining Night Cream
4
Best for All Skin Types

SkinCeuticals Retinol 0.5 Refining Night Cream

Credit: SkinCeuticals
Pros
  • Available in three different concentrations
  • Contains soothing chamomille
Cons
  • It's more expensive than other options on this list

Great for all skin types because it's available in three concentrations (0.3, 0.5, and 1.0 percent), allowing you to start low and ease into the strength optimal for your skin, says Jamal.

5
Best Drugstore for Eyes

RoC Retinol Correxion Under Eye Cream

Retinol Correxion Under Eye Cream
5
Best Drugstore for Eyes

RoC Retinol Correxion Under Eye Cream

Now 32% Off
Credit: RoC
Pros
  • Affordable
  • Reduces look of dark circles
Cons
  • Applying retinol around the eyes can be tricky

"It gently reduces the appearance of fine lines, crow's-feet wrinkles, and dark circles," says Sobel. "It's made with a milder strength of retinol and contains hyaluronic acid to help bind essential moisture in your skin to re-plump wrinkles."

6
Best for Fine Lines

Alastin Renewal Retinol

Renewal Retinol
6
Best for Fine Lines

Alastin Renewal Retinol

Credit: Alastin
Pros
  • Well-tolerated
  • Moisturizing
  • Protects against oxidative stress
Cons
  • It's more expensive than other options on this list

"Since aging skin is often dehydrated and has difficulty tolerating more harsh formulations, I recommend Alastin Renewal Retinol 0.5 percent as a well-tolerated but effective retinol," says dermatologist Melissa K. Levin, MD. "It combines moisturizing ingredients such as glycerin, oat kernel extract, bisabolol, ceramides, and antioxidants, such as co-enzyme Q10. It also contains a snow mushroom extract that helps further hydrate the skin."

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7

SkinMedica Retinol Complex 0.25

Retinol Complex 0.25
7

SkinMedica Retinol Complex 0.25

Credit: SkinMedica
Pros
  • Safe to use near eyes
Cons
  • It's more expensive than other options on this list

"I counsel my patients to take special care when applying any product close to the eyes, as skin in that area can be very sensitive," says Engelman. "This is a bit more moisturizing and can serve as a buffer to the potential irritation of vitamin A."

8
Best for Beginners

Avene Retrinal 0.1 Intensive Cream

Retrinal 0.1 Intensive Cream
8
Best for Beginners

Avene Retrinal 0.1 Intensive Cream

Credit: Avene
Pros
  • Gentle formulation
Cons
  • It's more expensive than other options on this list

"This contains retinaldehyde, a gentle form of retinol, which is great for more sensitive skin types and those who are just getting acclimated with retinoids," says Sobel.

9
Best Refillable

Charlotte Tilbury Refillable Magic Night Moisturizer

Refillable Magic Night Moisturizer
9
Best Refillable

Charlotte Tilbury Refillable Magic Night Moisturizer

Credit: Charlotte Tilbury
Pros
  • Sustainable packaging
Cons
  • It's a splurge

"I love this night cream because it has a beautiful texture and works quickly to hydrate, plump, and smooth the skin while you sleep," says Engleman. The blend of time-released retinol, plant stem cells, and vitamin E offers anti-aging benefits over time.

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10
Best for Acne

Differin Acne Treatment Gel

Acne Treatment Gel
10
Best for Acne

Differin Acne Treatment Gel

Now 40% Off
Credit: Differin
Pros
  • Prevents and targets acne
  • Reduces acne scarring
  • Affordable
Cons
  • May be irritating for very sensitive skin

"Differin was previously available only through prescription, but the 0.1 percent concentration is now available over the counter," says Sobel. "This works primarily to address acne and acne scars but also helps restore the skin’s tone and texture."

11
Best for Dry Skin

Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum

Retinol Ceramide Capsules Line Erasing Night Serum
11
Best for Dry Skin

Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum

Now 11% Off
Credit: Elizabeth Arden
Pros
  • Moisturizing
Cons
  • Some reviewers don't like the capsule packaging

If you have dry skin, these Elizabeth Arden capsules work incredibly well. They are formulated with ceramides, which help hydrate and can combat some of the irritating and drying effects of retinol. And the formula has olive, sunflower, and avocado oils for additional hydration.

12
Best Retinol Alternative

Glo Skin Beauty Bio-Renew EGF Cream

Bio-Renew EGF Cream
12
Best Retinol Alternative

Glo Skin Beauty Bio-Renew EGF Cream

Credit: Glo Skin Beauty
Pros
  • Suitable for all skin types
Cons
  • It's a splurge

Engleman helped co-create this formula for those who can't tolerate retinol's irritating side effects. "It contains a blend of phyto-retinols (including bakuchiol), along with vegan epidermal growth factor and bio-recovery peptides," she says. "The formula is suitable for all skin types and performed extremely well in clinical trials, showing significant anti-aging, reparative, and moisturizing results."

Headshot of Genesis Rivas
Genesis Rivas

Genesis Rivas is the Beauty Editor at Oprah Daily, where she covers hair, makeup, skin, nails, and more. Before joining the Oprah Daily team, she wrote for several publications, including InStyle, Real Simple, and Shape. When she’s not testing, researching, and writing fun and educational beauty content, you can find her dancing and eating her way through New York City. Follow her on Instagram or TikTok

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